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- Dokumenttyp:
- Journal Article
- Autor(en):
- McTavish, Sean; Van, Anh T; Peeters, Johannes M; Weiss, Kilian; Harder, Felix N; Makowski, Marcus R; Braren, Rickmer F; Karampinos, Dimitrios C
- Titel:
- Partial Fourier in the presence of respiratory motion in prostate diffusion-weighted echo planar imaging.
- Abstract:
- PURPOSE: To investigate the effect of respiratory motion in terms of signal loss in prostate diffusion-weighted imaging (DWI), and to evaluate the usage of partial Fourier in a free-breathing protocol in a clinically relevant b-value range using both single-shot and multi-shot acquisitions. METHODS: A controlled breathing DWI acquisition was first employed at 3 T to measure signal loss from deep breathing patterns. Single-shot and multi-shot (2-shot) acquisitions without partial Fourier (no pF) and with partial Fourier (pF) factors of 0.75 and 0.65 were employed in a free-breathing protocol. The apparent SNR and ADC values were evaluated in 10 healthy subjects to measure if low pF factors caused low apparent SNR or overestimated ADC. RESULTS: Controlled breathing experiments showed a difference in signal coefficient of variation between shallow and deep breathing. In free-breathing single-shot acquisitions, the pF 0.65 scan showed a significantly (p < 0.05) higher apparent SNR than pF 0.75 and no pF in the peripheral zone (PZ) of the prostate. In the multi-shot acquisitions in the PZ, pF 0.75 had a significantly higher apparent SNR than 0.65 pF and no pF. The single-shot pF 0.65 scan had a significantly lower ADC than single-shot no pF. CONCLUSION: Deep breathing patterns can cause intravoxel dephasing in prostate DWI. For single-shot acquisitions at a b-value of 800 s/mm2, any potential risks of motion-related artefacts at low pF factors (pF 0.65) were outweighed by the increase in signal from a lower TE, as shown by the increase in apparent SNR. In multi-shot acquisitions however, the minimum pF factor should be larger, as shown by the lower apparent SNR at low pF factors.
- Zeitschriftentitel:
- MAGN RESON MATER PHY
- Jahr:
- 2024
- Volltext / DOI:
- doi:10.1007/s10334-024-01162-x
- PubMed:
- http://view.ncbi.nlm.nih.gov/pubmed/38743376
- Print-ISSN:
- 0968-5243
- TUM Einrichtung:
- Institut für Diagnostische und Interventionelle Radiologie (Prof. Makowski)
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