Echocardiographic evaluation of left ventricular function using an automated analysis algorithm is feasible for beginners and experts: comparison with invasive and non-invasive methods.

Nicol, Philipp; Rank, Andreas; Lenz, Tobias; Schürmann, Friederike; Syryca, Finn; Trenkwalder, Teresa; Reinhard, Wibke; Adolf, Rafael; Hadamitzky, Martin; Kastrati, Adnan; Joner, Michael; Schunkert, Heribert; Engel, Leif-Christopher

doi:10.1007/s12574-022-00590-9

2023

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Document type:: Journal Article; Research Support, Non-U.S. Gov't
Author(s):: Nicol, Philipp; Rank, Andreas; Lenz, Tobias; Schürmann, Friederike; Syryca, Finn; Trenkwalder, Teresa; Reinhard, Wibke; Adolf, Rafael; Hadamitzky, Martin; Kastrati, Adnan; Joner, Michael; Schunkert, Heribert; Engel, Leif-Christopher
Title:: Echocardiographic evaluation of left ventricular function using an automated analysis algorithm is feasible for beginners and experts: comparison with invasive and non-invasive methods.
Abstract:: AIMS: Echocardiographic measurement of left ventricular function using a user-friendly automated three-dimensional algorithm is highly attractive as it promises quick and accurate diagnosis, circumventing limitations associated with visual estimation or manual biplane measurements. We sought to assess the feasibility and correlation of such automated analysis with clinically established methods. METHODS: A total of 198 patients undergoing transthoracic echocardiography (TTE) with assessment of left ventricular parameters by automated software algorithm (Philips 3D-Heartmodel; 3D-HM) which additionally had either left ventricular angiography (LVA) or cardiac magnetic resonance (CMR) within 24 h of the TTE examination were analyzed. Left ventricular parameters (left ventricular end-diastolic volume, LVEDV, left ventricular end-systolic volume, LVESV as well as left ventricular ejection fraction, LVEF) were compared between 3D-HM, CMR and LVA. RESULTS: Correlation of left ventricular measurements was overall good to excellent and stronger for CMR (EF r = 0.824) than for LVA (EF r = 0.746). Unexperienced and expert clinicians yielded comparable good results. For CMR, highest correlation was detected in patients with BMI < 25 and excellent image quality. High agreement was seen between 3D-HM and CMR or LVA when stratifying patients according to heart failure categories. CONCLUSIONS: Echocardiographic quantification of left ventricular parameters using a software-based algorithm correlated well with established invasive and non-invasive modalities in the clinical setting, even for unexperienced clinicians. Such automated approaches are promising as they allow a reliable, more observer-independent as well as reproducible assessment of left ventricular function.
Journal title abbreviation:: J Echocardiogr
Year:: 2023
Journal volume:: 21
Journal issue:: 2
Pages contribution:: 65-73
Fulltext / DOI:: doi:10.1007/s12574-022-00590-9
Pubmed ID:: http://view.ncbi.nlm.nih.gov/pubmed/36227498
Print-ISSN:: 1349-0222
TUM Institution:: Klinik für Herz- und Kreislauferkrankungen im Erwachsenenalter (Prof. Schunkert)
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mediaTUM Gesamtbestand Einrichtungen Schools TUM School of Medicine and Health Departments Clinical Medicine Lehr- und Forschungskooperationen mit den Kliniken und Instituten am Deutschen Herzzentrum Klinik für Herz- und Kreislauferkrankungen im Erwachsenenalter (DHM) (Prof. Schunkert)2023