Where have all the Orais gone? Commentary on "Orai1 channels are essential for amplification of glutamate-evoked Ca2+ signals in dendritic spines to regulate working and associative memory".

Dokumenttyp:: Article; Journal Article; Research Support, Non-U.S. Gov't; Comment
Autor(en):: Hartmann, Jana; Chen-Engerer, Hsing-Jung; Konnerth, Arthur
Titel:: Where have all the Orais gone? Commentary on "Orai1 channels are essential for amplification of glutamate-evoked Ca2+ signals in dendritic spines to regulate working and associative memory".
Abstract:: Orai1 channels were reported as critical contributors to the Ca2+ signal in hippocampal neurons underlying synaptic plasticity associated with learning and memory. We discuss the results in view of conflicting other reports that stressed the roles of Orai2 channels but failed to detect functions of Orai1 channels in these neurons.
Zeitschriftentitel:: Cell Calcium
Jahr:: 2021
Band / Volume:: 96
Volltext / DOI:: doi:10.1016/j.ceca.2021.102372
PubMed:: http://view.ncbi.nlm.nih.gov/pubmed/33640627
Print-ISSN:: 0143-4160
TUM Einrichtung:: Institut für Neurowissenschaften
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