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- Dokumenttyp:
- Article
- Autor(en):
- Heitkamp, Melanie; Spanier, Bianca; von Korn, Pia; Knapp, Sebastian; Gross, Claudia; Haller, Bernhard; Halle, Martin
- Titel:
- Feasibility of a 12-Month Exercise Intervention in Postsurgical Colorectal Cancer Patients
- Abstract:
- Background. Extensive physical activity (PA; & GE; 18 MET*h/week, MET metabolic equivalent of tasks hours) postcancer diagnosis has shown favorable effects on colorectal cancer disease-free survival. However, the feasibility of introducing this high volume of PA in this patient group is unclear. Therefore, the aim of the F-PROTECT study was to evaluate the feasibility of extensive and prolonged PA (& GE; 18 MET*h/week over 12 months) in colorectal cancer patients with the primary objectives to (1) recruit 50 patients within 12 months and (2) reach an attendance rate of & GE; 70%. Methods. Single-armed, bicentric, prospective intervention study in colorectal cancer patients (& LE; 80 years; UICC II/III Union for International Cancer Control) after histopathological confirmed R0-resection who were consecutively recruited from visceral surgery units of 10 clinics in Germany. Recruitment rates were calculated using screening logs. Intervention was a 12-month endurance-focused exercise program with supervised and home-based training. Attendance rates defined as & GE; 70% participation in training sessions were calculated by training diaries. Results. Out of 521 patients who were screened for eligibility, 50 (23 female; 59 & PLUSMN; 10 years, UICC 44% II, 56% III; adjuvant chemotherapy 60%) were recruited within 15 months. Mean duration between surgery and first training was 103 & PLUSMN; 57 days. Training attendance rate was 64% (including 9 dropouts). Six (12%) participants reached & GE; 18 MET*h/week in & GE; 70% of training sessions between 4-12 months. 28 adverse events (n = 9 serious) occurred, however, were not assessed as training related. Conclusions. The present intervention involving a combination of supervised and home-based exercise training in postsurgical colorectal cancer patients was not feasible. Strategies specifically designed for this patient group must be developed and investigated to motivate long-term PA. Registration. The study was prospectively registered at clinicaltrials.gov ().
- Zeitschriftentitel:
- Transl Sports Med
- Jahr:
- 2023
- Band / Volume:
- 2023
- Volltext / DOI:
- doi:10.1155/2023/4488334
- TUM Einrichtung:
- Poliklinik für Präventive und Rehabilitative Sportmedizin
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